T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen.

doi:10.1084/jem.178.2.713

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Article

T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen.

The Journal of experimental medicine - 1 Aug 1993

Ehrich E W, Devaux B, Rock E P, Jorgensen J L, Davis M M, Chien Y H

Abstract excerpt

While recent evidence strongly suggests that the third complementarity determining regions (CDR3s) of T cell receptors (TCRs) directly contact antigenic peptides bound to major histocompatibility complex (MHC) molecules, the nature of other TCR contact(s) is less clear. Here we probe the extent t...

Topics

Amino Acid Sequence
Animals
Antigen-Presenting Cells
Antigens
CHO Cells
Cell Line
Cricetinae
Cytochrome c Group
Enterotoxins
Histocompatibility Antigens Class II
Hybridomas
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Peptides

Receptors, Antigen, T-Cell

Receptors, Antigen, T-Cell, alpha-beta

Staphylococcus aureus

T-Lymphocytes

Source

Open in PubMed Open full text

Identifiers

PMID: 8393480
DOI: 10.1084/jem.178.2.713
PMCID: PMC2191102

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8393480-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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T cell receptor interaction with peptide/major histocompatibility complex (MHC) and superantigen/MHC ligands is dominated by antigen.PMID 8393480Read ↗

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