Functional and phenotypic analysis of thymocytes in SCID mice. Evidence for functional response transitions before and after the SCID arrest point.

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Article

Functional and phenotypic analysis of thymocytes in SCID mice. Evidence for functional response transitions before and after the SCID arrest point.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 1993

Rothenberg E V, Chen D, Diamond R A

Abstract excerpt

Thymocytes from severe combined immune deficient (SCID) mice undergo developmental arrest at an early stage, before most TCR gene rearrangement. They therefore represent a natural test case to assess those aspects of T cell development that are TCR independent. Multiparameter flow cytometry was u...

Topics

Animals
Cell Division
Cells, Cultured
Interleukin-1
Interleukin-2
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Mice, SCID
Phenotype
Receptors, Interleukin-2
Receptors, Lymphocyte Homing
T-Lymphocytes

Source

Open in PubMed

Identifiers

PMID: 8376791

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8376791-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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