Article
Immune deficiency in SCID mice.
International reviews of immunology - 1 Jan 1996
Nonoyama S, Ochs H D
Abstract excerpt
Since the discovery of SCID mice in 1983, numerous studies utilizing these mice were carried out. These investigations can be classified into two major groups. First, the analysis of the immune defect has revealed defective V(D)J recombination and defective DNA double-strand break repair, and has...
Topics
- Animals
- DNA Repair
- DNA-Activated Protein Kinase
- DNA-Binding Proteins
- Lymphocyte Transfusion
- Mice
- Mice, SCID
- Mutation
- Protein Serine-Threonine Kinases
- Recombination, Genetic