Article
Simplified method of identifying severe combined immunodeficient (SCID) mice versus non-SCID mice by flow cytometric analysis of peripheral blood.
Cytometry - 1 Aug 1998
Murray S, Subramanian S, Bourdette D N, Jones R E
Abstract excerpt
Several studies have utilized simple breeding strategies to create new immunodeficient mouse strains from severe combined immunodeficient (SCID) mice and non-SCID mice with secondary traits in order to evaluate the involvement of lymphocytes and immune responses in a variety of processes. We util...
Topics
- Animals
- Antibodies, Monoclonal
- CD3 Complex
- Crosses, Genetic
- Female
- Flow Cytometry
- Fluorescent Antibody Technique, Direct
- Lymphocytes
- Male
- Mice
- Mice, Inbred Strains
- Mice, SCID
- Phenotype
- Severe Combined Immunodeficiency