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Article

Protein kinase C-beta is required for macrophage differentiation of human HL-60 leukemia cells.

The Journal of biological chemistry - 16 Sept 1994

Tonetti D A, Henning-Chubb C, Yamanishi D T, Huberman E

Abstract excerpt

The requirement for protein kinase C (PKC)-beta in phorbol 12-myristate 13-acetate (PMA)-induced macrophage differentiation of human HL-60 promyelocytic leukemia cells was studied by using the variant HL-525, which is deficient in PKC-beta and is resistant to PMA-induced differentiation. Transfecting these resistant HL-525 cells with expression vectors containing either PKC-beta I or PKC-beta II cDNA resulted in...

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Source

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PMID: 8083228

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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