Article
Antimutator mutations in the alpha subunit of Escherichia coli DNA polymerase III: identification of the responsible mutations and alignment with other DNA polymerases.
Genetics - 1 Aug 1993
Fijalkowska I J, Schaaper R M
Abstract excerpt
The dnaE gene of Escherichia coli encodes the DNA polymerase (alpha subunit) of the main replicative enzyme, DNA polymerase III holoenzyme. We have previously identified this gene as the site of a series of seven antimutator mutations that specifically decrease the level of DNA replication errors...
Topics
- Alleles
- Amino Acid Sequence
- Cloning, Molecular
- DNA Polymerase III
- DNA, Bacterial
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Sequence Alignment