Effects of Escherichia coli dnaE antimutator alleles in a proofreading-deficient mutD5 strain.

doi:10.1128/jb.177.20.5979-5986.1995

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Article

Effects of Escherichia coli dnaE antimutator alleles in a proofreading-deficient mutD5 strain.

Journal of bacteriology - 1 Oct 1995

Fijalkowska I J, Schaaper R M

Abstract excerpt

We have previously isolated seven mutants of Escherichia coli which replicate their DNA with increased fidelity. These mutants were isolated as suppressors of the elevated mutability of a mismatch-repair-defective mutL strain. Each mutant was shown to contain a single amino acid substitution in t...

Topics

Adenosine Triphosphatases
Alleles
Bacterial Proteins
DNA Polymerase III
DNA Replication
Escherichia coli
Escherichia coli Proteins
Models, Genetic
MutL Proteins
Mutagenesis
Sequence Analysis, DNA
Suppression, Genetic

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