Article
Spontaneous mutation in Escherichia coli containing the dnaE911 DNA polymerase antimutator allele.
Genetics - 1 Oct 1994
Oller A R, Schaaper R M
Abstract excerpt
We have previously isolated mutants of Escherichia coli that replicate their DNA with increased fidelity. These mutants have a mutation in the dnaE gene, encoding the alpha subunit of DNA polymerase III. They were isolated in a mismatch-repair-defective mutL background, in which mutations can be considered to represent uncorrected DNA replication errors. In the present study we analyze the effect of one of these...
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