Article
Effect of Escherichia coli dnaE antimutator mutants on mutagenesis by the base analog N4-aminocytidine.
Mutation research - 18 Jun 1998
Schaaper R M, Dunn R L
Abstract excerpt
Previous studies in our laboratory have identified a set of mutations in the Escherichia coli dnaE gene that confer increased accuracy of DNA replication (antimutators). The dnaE gene encodes the polymerase subunit of DNA polymerase III holoenzyme that replicates the E. coli chromosome. Here, we...
Topics
- Alleles
- Antimutagenic Agents
- Chromosomes, Bacterial
- Cytidine
- DNA Polymerase III
- Dose-Response Relationship, Drug
- Escherichia coli
- Mutagens
- Mutation