Article
Embryonic stem (ES) cells lacking functional c-jun: consequences for growth and differentiation, AP-1 activity and tumorigenicity.
Oncogene - 1 Dec 1992
Hilberg F, Wagner E F
Abstract excerpt
The proto-oncogene c-jun encodes the major component of the transcription factor AP-1 and is thought to have important functions in cell proliferation and differentiation as well as in the cellular response to a variety of external stimuli. To investigate directly the role of c-jun in growth, dif...
Topics
- Alleles
- Animals
- Base Sequence
- Cell Differentiation
- Cell Division
- Cell Line
- Cell Transformation, Neoplastic
- Chloramphenicol O-Acetyltransferase
- DNA
- Embryo, Mammalian
- Gene Expression
- Genes, jun
- Genetic Vectors
- Mice
- Mice, Inbred Strains
- Molecular Sequence Data
- Neoplasm Transplantation
- Oligodeoxyribonucleotides