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Article

Crumbs and stardust act in a genetic pathway that controls the organization of epithelia in Drosophila melanogaster.

Developmental biology - 1 Sept 1993

Tepass U, Knust E

Abstract excerpt

We provide evidence that the genes crumbs (crb) and stardust (sdt) encode critical components of a pathway that acts at the apical pole of epithelial cells to control the cytoarchitecture of ectodermally derived epithelia of the Drosophila embryo. We describe the developmental defects caused by s...

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Identifiers

PMID: 8365569
DOI: 10.1006/dbio.1993.1243

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-8365569-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Crumbs and stardust act in a genetic pathway that controls the organization of epithelia in Drosophila melanogaster.PMID 8365569Read ↗

crumbs and stardust, two genes of Drosophila required for the development of epithelial cell polarity.Semantic proximity Read ↗

Drosophila Stardust interacts with Crumbs to control polarity of epithelia but not neuroblasts.Semantic proximity Read ↗

Crumbs, Moesin and Yurt regulate junctional stability and dynamics for a proper morphogenesis of the Drosophila pupal wing epithelium.Semantic proximity Read ↗

Multiple domains of Stardust differentially mediate localisation of the Crumbs-Stardust complex during photoreceptor development in Drosophila.Semantic proximity Read ↗

CRUMBS is involved in the control of apical protein targeting during Drosophila epithelial development.Semantic proximity Read ↗

Crumbs controls epithelial integrity by inhibiting Rac1 and PI3K.Semantic proximity Read ↗

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia.Semantic proximity Read ↗

Unique cell biological profiles of retinal disease-causing missense mutations in the polarity protein Crumbs.Semantic proximity Read ↗

Unraveling the genetic complexity of Drosophila stardust during photoreceptor morphogenesis and prevention of light-induced degeneration.Semantic proximity Read ↗

Integrated activity of PDZ protein complexes regulates epithelial polarity.Semantic proximity Read ↗

Drosophila Crumbs is a positional cue in photoreceptor adherens junctions and rhabdomeres.Semantic proximity Read ↗

Crumbs is required to achieve proper organ size control during Drosophila head development.Semantic proximity Read ↗

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