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Article

Evolution of the class II major histocompatibility complex alleles in higher primates.

Immunological reviews - 1 Feb 1990

Kasahara M, Klein D, Fan W M, Gutknecht J

Abstract excerpt

We have shown that chimpanzees and gorillas have DRB alleles very similar to those of humans. The existence of similar DRB alleles in the different species of higher primates cannot be accounted for by convergent evolution of unrelated alleles that arose independently after the speciation. We the...

Topics

Alleles
Animals
Base Sequence
Biological Evolution
HLA-D Antigens
HLA-DR Antigens
Histocompatibility Antigens Class II
Hominidae
Humans
Molecular Sequence Data
Phylogeny
Polymorphism, Genetic

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Identifiers

PMID: 2180812
DOI: 10.1111/j.1600-065x.1990.tb00037.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2180812-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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