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Article

Role of BRCA1 mutation screening in the management of familial ovarian cancer.

American journal of obstetrics and gynecology - 1 Sept 1996

Berchuck A, Cirisano F, Lancaster J M, Schildkraut J M, Wiseman R W, Futreal A, Marks J R

Abstract excerpt

Families with multiple cases of ovarian cancer have long been observed, and in the past prophylactic oophorectomy has been advocated for women with a history of ovarian cancer in two first-degree relatives. It is now thought that > 90% of familial ovarian cancer is due to inherited mutations in the BRCA1 breast-ovarian cancer susceptibility gene on chromosome 17q. BRCA1 testing is being performed in several...

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Share to Chromosomes, Human, Pair 17
Share to BRCA1 gene

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 8828444
DOI: 10.1053/ob.1996.v175.a74288

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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