p53 gene mutations in Chinese human testicular seminoma.

Article

p53 gene mutations in Chinese human testicular seminoma.

The Journal of urology - 1 Sept 1993

Ye D W, Zheng J, Qian S X, Ma Y, Zheng X, Li D, Gu S

Abstract excerpt

Genomic deoxyribonucleic acid from 17 primary human testicular seminomas was screened for the presence of mutations in exons 5 to 8 of gene p53, using the single strand conformation polymorphism assay, followed by direct deoxyribonucleic acid sequencing. The p53 mutations in 1 allele leading to a...

Topics

Base Sequence
China
DNA Mutational Analysis
Dysgerminoma
Exons
Genes, p53
Humans
Male
Molecular Sequence Data
Mutation
Polymerase Chain Reaction
Polymorphism, Genetic
Testicular Neoplasms

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