Article
Mutations of p53 in Wilms' tumors.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 1995
Takeuchi S, Bartram C R, Ludwig R, Royer-Pokora B, Schneider S, Imamura J, Koeffler H P
Abstract excerpt
Mutations of p53 frequently occur in a wide variety of cancers including lung, breast, gastrointestinal, brain, and hematologic malignancies. These alterations apparently contributed to development of the malignant phenotype. Wilms' tumor is one of the most common solid tumors in childhood. The frequency of p53 alterations in this tumor is unknown. We analyzed 66 Wilms' tumor samples for p53 mutations by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
