Article
Mutations of p53 in Wilms' tumors.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jun 1995
Takeuchi S, Bartram C R, Ludwig R, Royer-Pokora B, Schneider S, Imamura J, Koeffler H P
Abstract excerpt
Mutations of p53 frequently occur in a wide variety of cancers including lung, breast, gastrointestinal, brain, and hematologic malignancies. These alterations apparently contributed to development of the malignant phenotype. Wilms' tumor is one of the most common solid tumors in childhood. The f...
Topics
- Base Sequence
- Child
- Exons
- Genes, p53
- Humans
- Immunohistochemistry
- Kidney Neoplasms
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction
- Polymorphism, Single-Stranded Conformational
- Wilms Tumor
