Article
Identification of a G1-S-phase-regulated region in the human thymidine kinase gene promoter.
Molecular and cellular biology - 1 Jul 1990
Roehl H H, Conrad S E
Abstract excerpt
We have identified a regulatory region in the human thymidine kinase gene promoter. A set of promoter deletion mutants was constructed, linked to the bacterial neomycin resistance gene, and stably transfected into Rat3 cells. It was shown that the region between 135 and 67 base pairs upstream of the cap site is required for conveying G1-S-phase regulation to the linked neo gene. In addition, primer extension...
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