Article
A novel TCTG(G/C) direct repeat and an A/T-rich HMG2-binding site control the expression of the rat cardiac troponin T gene.
Journal of molecular and cellular cardiology - 1 Dec 2002
Wang Qin, Li-Chun Lin Jenny, Jung-Ching Lin Jim
Abstract excerpt
We previously showed that the rat cardiac troponin T proximal promoter (-497bp from the transcriptional start site) was sufficient to confer cardiac-specific expression of a reporter gene in both cultured cardiomyocytes and transgenic mice. This promoter consists of two cis-regulatory modules with high sequence similarity. Nucleotides from -319 to -289 (termed D2) and nucleotides from -249 to -209 (termed F41)...
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