Article
Hepatocyte nuclear phenotype: the cross-talk between anabolic androgenic steroids and exercise in transgenic mice.
Histology and histopathology - 1 Nov 2008
Fontana Karina, Aldrovani Marcela, de Paoli Flávia, Oliveira Helena C F, de Campos Vidal Benedicto, da Cruz-Höfling Maria Alice
Abstract excerpt
The growing and indiscriminate use of high doses of anabolic androgenic steroid (AAS) among youth and athletes has raised serious concerns about its hepatotoxic effects. Herein, the influence of AAS in the nuclear phenotype of hepatocytes was investigated in sedentary and trained mice heterozygous for the human CETP (cholesteryl ester transfer protein) transgene and for LDL-receptor null allele (CETP+/-LDLr+/-)...
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