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Article

Quantitative comparison of initiation and mutation phenotypes in hepatocytes of the analbuminemic rat.

Japanese journal of cancer research : Gann - 1 Feb 1993

Dragan Y P, Laufer C, Koleske A J, Drinkwater N, Pitot H C

Abstract excerpt

The potential relationship between mutagenesis and carcinogenesis has been examined in the Nagase analbuminemic rat treated with a single dose of benzo[a]pyrene, an incomplete liver carcinogen. The apparent mutation rate at the albumin locus was calculated by determining the number of hepatocytes expressing a cross-reactive product of albumin in analbuminemic rats treated with benzo[a]pyrene. The rate of...

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Identifiers

PMID: 8463134
DOI: 10.1111/j.1349-7006.1993.tb02852.x
PMCID: PMC5919122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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