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Article

Detection of K-ras mutation in sputum by mutant-allele-specific amplification (MASA).

Human mutation - 1 Jan 1993

Takeda S, Ichii S, Nakamura Y

Abstract excerpt

From 10 to 30% of lung carcinomas examined to date contain mutant K-ras genes. We report here that the mutant-allele-specific amplification (MASA) method may be useful for detection of the K-ras mutations in cells obtained from the sputum of patients with lung cancer. The PCR product from one of five patients revealed an alteration when mixed oligonucleotides representing variants of the second letter at codon 12...

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Identifiers

PMID: 8318987
DOI: 10.1002/humu.1380020209

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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