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Article

Allele-specific detection of K-ras oncogene expression in human non-small-cell lung carcinomas.

International journal of cancer - 22 Apr 1991

Slebos R J, Habets G G, Evers S G, Mooi W J, Rodenhuis S

Abstract excerpt

Point mutations in codon 12 of the K-ras oncogene are frequent in human lung adenocarcinomas. To study the expression of the K-ras gene in these tumors we have developed a mRNA detection technique based on the polymerase chain reaction (PCR). By this technique, K-ras expression can be detected semi-quantitatively in samples of less than 100 ng total RNA. Hybridization of the amplified cDNA sequences with...

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Identifiers

PMID: 1850383
DOI: 10.1002/ijc.2910480110

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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