Article
Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2.
The EMBO journal - 1 Feb 1994
Stewart E, Kobayashi H, Harrison D, Hunt T
Abstract excerpt
The specific and rapid destruction of cyclins A and B during mitosis is their most remarkable property. A short peptide motif of approximately 10 amino acids near the N-terminus, known as the destruction box, is absolutely required for programmed proteolysis. In this paper we show that although t...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- CDC2 Protein Kinase
- Conserved Sequence
- Cyclins
- DNA
- Humans
- Molecular Sequence Data
- Mutation
- Phosphorylation
- Precipitin Tests
- Xenopus