Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The roles of Drosophila cyclins A and B in mitotic control.

Cell - 4 May 1990

Lehner C F, O'Farrell P H

Abstract excerpt

We have cloned, sequenced, and characterized the expression of a Drosophila cyclin B gene. The independent evolutionary conservation of A- and B-type cyclins implies that they have distinct roles. Indeed, in mutant embryos deficient in cyclin A, cells that accumulate only cyclin B do not enter mi...

Topics

Amino Acid Sequence
Animals
Antibodies
Base Sequence
Biological Evolution
Cell Cycle
Cloning, Molecular
Cyclins
Drosophila
Embryo, Nonmammalian
Gene Expression
Genes
Insect Hormones

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Interphase

Invertebrate Hormones

Mitosis

Molecular Sequence Data

Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 2139805
DOI: 10.1016/0092-8674(90)90535-m
PMCID: PMC2753431

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2139805-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The roles of Drosophila cyclins A and B in mitotic control.PMID 2139805Read ↗

Drosophila Cyclin B3 is required for female fertility and is dispensable for mitosis like Cyclin B.Semantic proximity Read ↗

Synergistic action of Drosophila cyclins A and B during the G2-M transition.Semantic proximity Read ↗

Characterization and Expression of Mammalian Cyclin B3, a Prepachytene Meiotic CyclinSemantic proximity Read ↗

Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancerSemantic proximity Read ↗

Promiscuity rules? The dispensability of cyclin E and Cdk2.Semantic proximity Read ↗

Destruction of Xenopus cyclins A and B2, but not B1, requires binding to p34cdc2.Semantic proximity Read ↗

Exploring the role of Drosophila cyclin A in the regulation of S phase.Semantic proximity Read ↗

Caenorhabditis elegans cyclin A- and B-type genes: a cyclin A multigene family, an ancestral cyclin B3 and differential germline expression.Semantic proximity Read ↗

Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero.Semantic proximity Read ↗

Cyclin A1, the alternative A-type cyclin, contributes to G1/S cell cycle progression in somatic cellsSemantic proximity Read ↗

Human cyclins B1 and B2 are localized to strikingly different structures: B1 to microtubules, B2 primarily to the Golgi apparatus.Semantic proximity Read ↗

Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.