Article
Proteolysis and DNA replication: the CDC34 requirement in the Xenopus egg cell cycle.
Science (New York, N.Y.) - 12 Sept 1997
Yew P R, Kirschner M W
Abstract excerpt
The cell division cycle gene, CDC34, is required for ubiquitin-mediated degradation of G1 regulators and cell cycle progression through the transition from G1 to S phase in budding yeast. A CDC34 requirement for S phase onset in higher eukaryotes has not been established. Studies of the simple embryonic cell cycle of Xenopus laevis eggs demonstrated that Cdc34p in a large molecular size complex was required in...
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