Article
Proteolysis and DNA replication: the CDC34 requirement in the Xenopus egg cell cycle.
Science (New York, N.Y.) - 12 Sept 1997
Yew P R, Kirschner M W
Abstract excerpt
The cell division cycle gene, CDC34, is required for ubiquitin-mediated degradation of G1 regulators and cell cycle progression through the transition from G1 to S phase in budding yeast. A CDC34 requirement for S phase onset in higher eukaryotes has not been established. Studies of the simple em...
Topics
- Anaphase-Promoting Complex-Cyclosome
- Animals
- CDC2-CDC28 Kinases
- Cell Cycle Proteins
- Cell Nucleus
- Chromosomes
- Cyclin-Dependent Kinase 2
- Cyclin-Dependent Kinase Inhibitor p27
- Cyclin-Dependent Kinases
- Cyclins
- DNA Replication
- Enzyme Inhibitors
- Humans
- Ligases
- Microtubule-Associated Proteins
- Mitosis
- Mutation
- Ovum