2-Aminofluorene metabolism and DNA adduct formation by mononuclear leukocytes from rapid and slow acetylator mouse strains.

doi:10.1093/carcin/15.2.353

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Article

2-Aminofluorene metabolism and DNA adduct formation by mononuclear leukocytes from rapid and slow acetylator mouse strains.

Carcinogenesis - 1 Feb 1994

Levy G N, Chung J G, Weber W W

Abstract excerpt

Following exposure of mice to the arylamine carcinogen 2-aminofluorene, DNA-carcinogen adducts can be found in the target tissues liver and bladder, and also in circulating leukocytes. Evidence is presented here that mouse mononuclear leukocytes (MNL) are capable of metabolizing 2-aminofluorene t...

Topics

4-Aminobenzoic Acid
Acetylation
Animals
Carcinogens
Cells, Cultured
DNA Damage
Fluorenes
Genotype
Leukocytes, Mononuclear
Mice
Mice, Inbred C57BL

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