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Article

DNA adduct levels in congenic rapid and slow acetylator mouse strains following chronic administration of 4-aminobiphenyl.

Carcinogenesis - 1 Oct 1992

Flammang T J, Couch L H, Levy G N, Weber W W, Wise C K

Abstract excerpt

4-Aminobiphenyl (4-ABP) is a human and mouse bladder carcinogen. Epidemiological studies have shown that individuals with a slow acetylator phenotype, especially those exposed to high levels of carcinogenic aromatic amines, show an increased susceptibility to bladder cancer. In order to determine...

Topics

Acetylation
Aminobiphenyl Compounds
Animals
Autoradiography
DNA
DNA Damage
Deoxyguanosine
Female
Genotype
Isotope Labeling
Liver
Male
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C57BL

Phenotype

Phosphorus Radioisotopes

Time Factors

Urinary Bladder

Source

Identifiers

PMID: 1423849
DOI: 10.1093/carcin/13.10.1887

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1423849-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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DNA adduct levels in congenic rapid and slow acetylator mouse strains following chronic administration of 4-aminobiphenyl.PMID 1423849Read ↗

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