Article
Polymorphic acetylation of arylamines and DNA-adduct formation.
Princess Takamatsu symposia - 1 Jan 1990
Weber W W, Levy G N, Martell K J
Abstract excerpt
Inbred mouse strains congenic for rapid and slow N-acetyltransferase (NAT) (A.B6, rapid and B6.A, slow) were used to separate the effect of the NAT polymorphism from the influence of other genetically polymorphic enzymes on DNA adduct formation induced by exposure to arylamine carcinogens. Adduct...
Topics
- Acetylation
- Acetyltransferases
- Age Factors
- Animals
- DNA
- DNA Damage
- Fluorenes
- Genotype
- Male
- Mice
- Mice, Inbred A
- Mice, Inbred C57BL
- Mutagens
- Sex Factors
- Urinary Bladder