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Article

Retinoblastoma gene mutation in primary human renal cell carcinoma.

Oncology research - 1 Jan 1995

Shuin T, Torigoe S, Kubota Y, Kishida T, Hosaka M, Horikoshi T, Yao M, Kondo K, Sakai N, Danenberg K

Abstract excerpt

We searched for possible mutations in the E2F-binding region of retinoblastoma gene in primary human renal cell carcinomas, using polymerase chain reaction and single-strand conformational polymorphism analysis of RNA. Retinoblastoma gene mutation was detected in 1 of 21 cases (5%). DNA sequencing of the polymerase chain reaction product verified that this case had a 6-base deletion at the beginning of exon 8....

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PMID: 7579728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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