N-acetylation phenotyping using dapsone in a Jordanian population.

doi:10.1111/j.1365-2125.1991.tb03901.x

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Article

N-acetylation phenotyping using dapsone in a Jordanian population.

British journal of clinical pharmacology - 1 Sept 1991

Irshaid Y M, al-Hadidi H F, Abuirjeie M A, Rawashdeh N M

Abstract excerpt

1. The N-acetylation of dapsone (DDS) was studied in 160 unrelated healthy Jordanian volunteers. 2. The frequency of slow acetylators determined using the plasma monoacetyldapsone (MADDS) to DDS ratio (MADDS/DDS), was 67.5% with a 95% confidence interval of 59 to 76%. Slow acetylators had an acet...

Topics

Acetylation
Adolescent
Adult
Dapsone
Female
Humans
Jordan
Male
Middle Aged
Phenotype
Reference Values

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