Article
A single sample saliva test to determine acetylator phenotype.
British journal of clinical pharmacology - 1 Nov 1996
Hutchings A D, Routledge P A
Abstract excerpt
A comparison was made between the results of acetylator phenotyping by determination of the acetylisoniazid to isoniazid (AcINH/INH) concentration ratio in plasma and in saliva 3 h after oral administration of isoniazid (200mg). In the 154 subjects studied, 68 (44%) were fast acetylators (AcINH/INH ratio > 1.5) using the plasma ratio. In all subjects the saliva AcINH/INH ratio was also > 1.5. Eighty-five of the...
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