Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An 'elaborated' pseudoknot is required for high frequency frameshifting during translation of HCV 229E polymerase mRNA.

Nucleic acids research - 25 Dec 1993

Herold J, Siddell S G

Abstract excerpt

The RNA polymerase gene (gene 1) of the human coronavirus 229E is approximately 20 kb in length and is located at the 5' end of the positive-strand genomic RNA. The coding sequence of gene 1 is divided into two large open reading frames, ORF1a and ORF1b, that overlap by 43 nucleotides. In the region of the ORF1a/ORF1b overlap, the genomic RNA displays two elements that are known to mediate (-1) ribosomal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Mutagenesis, Site-Directed

Share to Mutation

Share to Nucleic Acid Conformation

Share to RNA, Viral

Source

Open in PubMed Open full text

Identifiers

PMID: 8290341
DOI: 10.1093/nar/21.25.5838
PMCID: PMC310462

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An 'elaborated' pseudoknot is required for high frequency frameshifting during translation of HCV 229E polymerase mRNA.PMID 8290341Read ↗

A Computational and Biochemical Study of -1 Ribosomal Frameshifting in Human mRNAsSemantic proximity Read ↗

An atypical RNA pseudoknot stimulator and an upstream attenuation signal for -1 ribosomal frameshifting of SARS coronavirusSemantic proximity Read ↗

A conserved predicted pseudoknot in the NS2A-encoding sequence of West Nile and Japanese encephalitis flaviviruses suggests NS1' may derive from ribosomal frameshiftingSemantic proximity Read ↗

Structure-altering mutations of the SARS-CoV-2 frameshifting RNA element.Semantic proximity Read ↗

Functional analysis of the SRV-1 RNA frameshifting pseudoknot.Semantic proximity Read ↗

SARS-CoV-2 ribosomal frameshifting pseudoknot: Improved secondary structure prediction and detection of inter-viral structural similaritySemantic proximity Read ↗

RNA pseudoknots: translational frameshifting and readthrough on viral RNAs.Semantic proximity Read ↗

RNA dimerization plays a role in ribosomal frameshifting of the SARS coronavirus.Semantic proximity Read ↗

Regulation of -1 ribosomal frameshifting directed by cocksfoot mottle sobemovirus genome.Semantic proximity Read ↗

Identification of Hepta- and Octo-Uridine stretches as sole signals for programmed +1 and -1 ribosomal frameshifting during translation of SARS-CoV ORF 3a variants.Semantic proximity Read ↗

Solution structure of the pseudoknot of SRV-1 RNA, involved in ribosomal frameshifting.Semantic proximity Read ↗

Local structural and environmental factors define the efficiency of an RNA pseudoknot involved in programmed ribosomal frameshift process.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.