Article

SARS-CoV-2 ribosomal frameshifting pseudoknot: Improved secondary structure prediction and detection of inter-viral structural similarity

2020-09-15

Abstract excerpt

<h4> A bstract </h4> Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the COVID-19 pandemic; a pandemic of a scale that has not been seen in the modern era. Despite over 29 million reported cases and over 900, 000 deaths worldwide as of September 2020, herd immunity and widespread vaccination efforts by many experts are expected to be insufficient in addressing this crisis for the foresee...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: dbed01fe-3d9d-5dbc-953d-007926746883
DOI: 10.1101/2020.09.15.298604

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

SARS-CoV-2 ribosomal frameshifting pseudoknot: Improved secondary structure prediction and detection of inter-viral structural similarityDOI 10.1101/2020.09.15.298604Read

Shapify: Pathways to SARS-CoV-2 Frameshifting PseudoknotSemantic proximity Read

Modeling the structure of the frameshift-stimulatory pseudoknot in SARS-CoV-2 reveals multiple possible conformersSemantic proximity Read

Structural and functional conservation of the programmed −1 ribosomal frameshift signal of SARS coronavirus 2 (SARS-CoV-2)Semantic proximity Read

Structure-altering mutations of the SARS-CoV-2 frameshifting RNA element.Semantic proximity Read

Identification of RNA pseudoknot-binding ligand that inhibits the -1 ribosomal frameshifting of SARS-coronavirus by structure-based virtual screening.Semantic proximity Read

Crystal structure of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) frameshifting pseudoknot.Semantic proximity Read

Comprehensive in-vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanismsSemantic proximity Read

Anti-Frameshifting Ligand Active against SARS Coronavirus-2 Is Resistant to Natural Mutations of the Frameshift-Stimulatory Pseudoknot.Semantic proximity Read

A map of the SARS-CoV-2 RNA structuromeSemantic proximity Read

Stem loop binding protein promotes SARS-CoV-2 replication via -1 programmed ribosomal frameshiftingSemantic proximity Read

RNA dimerization plays a role in ribosomal frameshifting of the SARS coronavirus.Semantic proximity Read

Tying the Knot: Unraveling the Intricacies of the Coronavirus Frameshift PseudoknotSemantic proximity Read