Article
Regulation of -1 ribosomal frameshifting directed by cocksfoot mottle sobemovirus genome.
European journal of biochemistry - 1 Jun 2000
Lucchesi J, Mäkeläinen K, Merits A, Tamm T, Mäkinen K
Abstract excerpt
The polyprotein of Cocksfoot mottle virus (CfMV) is encoded by two overlapping open reading frames (ORFs). The putative replicase of CfMV is produced as a part of the polyprotein from ORF2b by the -1 ribosomal frameshifting mechanism. The signals leading to -1 ribosomal frameshifting directed by CfMV RNA are the slippery heptamer UUUAAAC and a stem-loop structure starting seven nucleotides downstream from the...
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