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Article

The B-subunit of DNA polymerase alpha-primase associates with the origin recognition complex for initiation of DNA replication.

Molecular and cellular biology - 1 Sept 2004

Uchiyama Masashi, Wang Teresa S-F

Abstract excerpt

The B-subunit (p70/Pol12p) of the DNA polymerase alpha-primase (Polalpha-primase) complex is thought to have a regulatory role in an early stage of S phase. We generated a panel of fission yeast thermosensitive mutants of the B-subunit (termed Spb70) to investigate its role in initiation of DNA replication by genetic and biochemical approaches. Here, we show that the fission yeast Spb70 genetically interacts and...

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Identifiers

PMID: 15314153
DOI: 10.1128/MCB.24.17.7419-7434.2004
PMCID: PMC506996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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