Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The B-subunit of DNA polymerase alpha-primase associates with the origin recognition complex for initiation of DNA replication.

Molecular and cellular biology - 1 Sept 2004

Uchiyama Masashi, Wang Teresa S-F

Abstract excerpt

The B-subunit (p70/Pol12p) of the DNA polymerase alpha-primase (Polalpha-primase) complex is thought to have a regulatory role in an early stage of S phase. We generated a panel of fission yeast thermosensitive mutants of the B-subunit (termed Spb70) to investigate its role in initiation of DNA r...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Cell Cycle Proteins
Share to DNA Polymerase I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primase

Share to DNA Replication

Share to Origin Recognition Complex

Share to Protein Subunits

Share to Temperature

Source

Open in PubMed Open full text

Identifiers

PMID: 15314153
DOI: 10.1128/MCB.24.17.7419-7434.2004
PMCID: PMC506996

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15314153-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The B-subunit of DNA polymerase alpha-primase associates with the origin recognition complex for initiation of DNA replication.PMID 15314153Read ↗

Role of fission yeast primase catalytic subunit in the replication checkpoint.Semantic proximity Read ↗

Analysis of fission yeast primase defines the checkpoint responses to aberrant S phase initiation.Semantic proximity Read ↗

The B subunit of the DNA polymerase alpha-primase complex in Saccharomyces cerevisiae executes an essential function at the initial stage of DNA replication.Semantic proximity Read ↗

Cell cycle-dependent phosphorylation and dephosphorylation of the yeast DNA polymerase alpha-primase B subunit.Semantic proximity Read ↗

A double-strand break repair component is essential for S phase completion in fission yeast cell cycling.Semantic proximity Read ↗

Fission yeast with DNA polymerase delta temperature-sensitive alleles exhibits cell division cycle phenotype.Semantic proximity Read ↗

The unstructured C-terminal tail of yeast Dpb11 (human TopBP1) protein is dispensable for DNA replication and the S phase checkpoint but required for the G2/M checkpoint.Semantic proximity Read ↗

Break-induced replication requires all essential DNA replication factors except those specific for pre-RC assembly.Semantic proximity Read ↗

Rad4TopBP1 associates with Srr2, an Spc1 MAPK-regulated protein, in response to environmental stress.Semantic proximity Read ↗

Cell cycle-dependent phosphorylation of the DNA polymerase epsilon subunit, Dpb2, by the Cdc28 cyclin-dependent protein kinase.Semantic proximity Read ↗

PCNA binding domains in all three subunits of yeast DNA polymerase δ modulate its function in DNA replication.Semantic proximity Read ↗

Analysis of origin recognition complex in saccharomyces cerevisiae by use of Degron mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.