Article
Fission yeast with DNA polymerase delta temperature-sensitive alleles exhibits cell division cycle phenotype.
Nucleic acids research - 11 Aug 1993
Francesconi S, Park H, Wang T S
Abstract excerpt
DNA polymerases alpha and delta are essential enzymes believed to play critical roles in initiation and replication of chromosome DNA. In this study, we show that the genes for Schizosaccharomyces pombe (S.pombe) DNA polymerase alpha and delta (pol alpha+ and pol delta+) are essential for cell vi...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- CDC2 Protein Kinase
- Cell Cycle
- Cell Division
- DNA Polymerase II
- DNA Polymerase III
- DNA-Directed DNA Polymerase
- Flow Cytometry
- Genetic Complementation Test
- Humans
- Molecular Sequence Data
- Mutation
- Phenotype
- Schizosaccharomyces
- Sequence Homology, Amino Acid
- Temperature