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Article

Fission yeast with DNA polymerase delta temperature-sensitive alleles exhibits cell division cycle phenotype.

Nucleic acids research - 11 Aug 1993

Francesconi S, Park H, Wang T S

Abstract excerpt

DNA polymerases alpha and delta are essential enzymes believed to play critical roles in initiation and replication of chromosome DNA. In this study, we show that the genes for Schizosaccharomyces pombe (S.pombe) DNA polymerase alpha and delta (pol alpha+ and pol delta+) are essential for cell viability. Disruption of either the pol alpha+ or pol delta+ gene results in distinct terminal phenotypes. The S.pombe...

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Identifiers

PMID: 8367300
DOI: 10.1093/nar/21.16.3821
PMCID: PMC309899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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