Article
Isolation and characterization of the fission yeast gene Sprpa12+ reveals that the conserved C-terminal zinc-finger region is dispensable for the function of its product.
Molecular & general genetics : MGG - 1 Feb 2001
Imazawa Y, Imai K, Yao Y, Yamamoto K, Hisatake K, Muramatsu M, Nogi Y
Abstract excerpt
RNA polymerase I of Saccharomyces cerevisiae contains a small subunit, A12.2, encoded by RPA12, that was previously shown to be involved in the assembly and/or stabilization of the largest subunit, A190, of RNA polymerase I. To examine whether an equivalent subunit is present in another eukaryotic RNA polymerase I, we have cloned a Schizosaccahromyces pombe cDNA that is able to complement the rpa12 mutation in S....
Topics
- Amino Acid Sequence
- Chromosomes, Fungal
- Conserved Sequence
- Genetic Complementation Test
- Genotype
- Molecular Sequence Data
- Plasmids
- Protein Subunits
- RNA Polymerase I
- Saccharomyces cerevisiae