The development of a mutation in the precore region of the hepatitis B virus in a chronically infected individual.

doi:10.1016/s0016-5085(94)95767-3

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Article

The development of a mutation in the precore region of the hepatitis B virus in a chronically infected individual.

Gastroenterology - 1 Jan 1994

Lee J H, Di Bisceglie A M, Baker B L, Zeldis J B

Abstract excerpt

Over a 15-year period, a white American woman was observed to have progressive hepatitis B that underwent hepatitis Be antigen (HBeAg) positivity to anti-HBe positivity with development of cirrhosis. This patient was found to have a non-sense mutation in the second codon of the pre-C region of th...

Topics

Adult
Antisense Elements (Genetics)
Base Sequence
Chronic Disease
DNA, Viral
Female
Hepatitis B
Hepatitis B Surface Antigens
Hepatitis B e Antigens
Hepatitis B virus
Humans
Molecular Probes
Molecular Sequence Data
Mutation

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