Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hepatitis may precede the occurrence of precore region mutation in hepatitis B virus genome during infection in young carriers.

Journal of medical virology - 1 Oct 1994

Nguyen X T, Fukuda R, Fukumoto S

Abstract excerpt

To understand when the mutation with a stop codon of precore region in hepatitis B virus genome occurs, the prevalence of the mutation of viral DNA clones propagated from sera of school-age carriers was investigated with respect to hepatitis B e antigen (HBeAg)/anti-HBe and sequential changes of mutants along HBeAg seroconversion were analyzed. Of 32 carriers aged 8-18 years, 14 HBeAg(+) patients had 2.2% mutant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Base Sequence
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Primers

Share to DNA, Viral

Share to Genome, Viral

Share to Molecular Sequence Data

Share to Mutation

Source

Identifiers

PMID: 7852961
DOI: 10.1002/jmv.1890440215

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hepatitis may precede the occurrence of precore region mutation in hepatitis B virus genome during infection in young carriers.PMID 7852961Read ↗

Precore region mutation in hepatitis B virus genome in early stage of infection: a study in hepatitis B e antigen-positive young carriers.Semantic proximity Read ↗

Point mutation in precore region of hepatitis B virus: sequential changes from 'wild' to 'mutant'.Semantic proximity Read ↗

Universal emergence of precore mutant hepatitis B virus along with seroconversion to anti-HBe irrespective of subsequent activity of chronic hepatitis B.Semantic proximity Read ↗

Low frequency of precore hepatitis B virus mutants in anti-hepatitis B e-positive reactivation after loss of hepatitis B e antigen in patients with chronic hepatitis B.Semantic proximity Read ↗

Hepatitis B core promoter or precore gene mutations related to age at seroconversion from hepatitis B e antigen to anti-hepatitis B e in Japanese children.Semantic proximity Read ↗

Lower mutation frequency of BCP/precore regions in e antigen-negative chronic HBV-infected children instead of adults patients.Semantic proximity Read ↗

Selection of a precore mutant of hepatitis B virus and reactivation of chronic hepatitis B acquired in childhood.Semantic proximity Read ↗

Genetic heterogeneity in the precore region of hepatitis B virus in hepatitis B e antigen-negative chronic hepatitis B patients: spontaneous seroconversion and interferon-induced seroconversion.Semantic proximity Read ↗

Evolution of precore/core promoter mutations in hepatitis B carriers with hepatitis B e antigen seroreversion.Semantic proximity Read ↗

Hepatitis B virus precore mutants are identical in carriers from various ethnic origins and are associated with a range of liver disease severity.Semantic proximity Read ↗

Clinical relevance of precore and basal core promoter variants of hepatitis B virus during natural hepatitis B e antigen seroconversion may be overstated.Semantic proximity Read ↗

Gradual accumulation of mutations in precore core region of HBV in patients with chronic active hepatitis: implications of clustering changes in a small region of the HBV core region.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.