Article
Hepatitis may precede the occurrence of precore region mutation in hepatitis B virus genome during infection in young carriers.
Journal of medical virology - 1 Oct 1994
Nguyen X T, Fukuda R, Fukumoto S
Abstract excerpt
To understand when the mutation with a stop codon of precore region in hepatitis B virus genome occurs, the prevalence of the mutation of viral DNA clones propagated from sera of school-age carriers was investigated with respect to hepatitis B e antigen (HBeAg)/anti-HBe and sequential changes of...
Topics
- Adolescent
- Alanine Transaminase
- Base Sequence
- Carrier State
- Child
- DNA Primers
- DNA, Viral
- Female
- Genome, Viral
- Hepatitis B
- Hepatitis B Antibodies
- Hepatitis B Surface Antigens
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Male
- Molecular Sequence Data
- Mutation