Interaction between splotch (Sp) and curly tail (ct) mouse mutants in the embryonic development of neural tube defects.

doi:10.1242/dev.119.1.113

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Article

Interaction between splotch (Sp) and curly tail (ct) mouse mutants in the embryonic development of neural tube defects.

Development (Cambridge, England) - 1 Sept 1993

Estibeiro J P, Brook F A, Copp A J

Abstract excerpt

The mouse mutations splotch (Sp) and curly tail (ct) both produce spinal neural tube defects with closely similar morphology, but achieve this by different embryonic mechanisms. To determine whether the mutants may interact during development, we constructed mice carrying both mutations. Double h...

Topics

Animals
Breeding
Ganglia, Spinal
Genotype
Mice
Mice, Mutant Strains
Mutation
Nervous System
Neural Crest
Neural Tube Defects

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