Article
Altered cell proliferation in the spinal cord of mouse neural tube mutants curly tail and Pax3 splotch-delayed.
Brain research. Developmental brain research - 20 Sept 1997
Keller-Peck C R, Mullen R J
Abstract excerpt
The mutant mouse strains splotch-delayed (Pax3Sp-d) and curly tail (ct) develop neural tube defects (NTDs) in the lumbosacral region of the neuraxis. Some research has focused on cell proliferation around the time of posterior neuropore closure in these mutants; however, there are little data on the effects of NTDs on cell birth at later stages of development. To investigate the role neural tube closure might...
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