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Article

p53 mutations in colorectal cancers in the patients of Metropolitan New York.

Anticancer research - 1 Jan 2000

van den Broek M H, Jhanwar S C, Fodde R, Chaganti R S, Meera Khan P M

Abstract excerpt

An unselected series of 19 colorectal adenocarcinomas obtained from patients treated by surgery at Memorial Sloan-Kettering Cancer Center (MSKCC), New York, USA was investigated for mutations in exons 5, 6, 7 and 8 of the p53 gene. Ten of the tumors revealed at least one somatic mutation either i...

Topics

Adenocarcinoma
Adult
Aged
Base Sequence
Codon
Colorectal Neoplasms
DNA Primers
Exons
Female
Genes, p53
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

New York City

Source

Identifiers

PMID: 8267380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8267380-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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