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Article

Different mutation profiles associated to P53 accumulation in colorectal cancer.

Gene - 10 May 2012

López Ignacio, P Oliveira Ligia, Tucci Paula, Alvarez-Valín Fernando, A Coudry Renata, Marín Mónica

Abstract excerpt

The tumor suppressor TP53 gene is one of the most frequently mutated in different types of human cancer. Particularly in colorectal cancer (CRC), it is believed that TP53 mutations play a role in the adenoma-carcinoma transition of tumors during pathological process. In order to analyze TP53 expressed alleles in CRC, we examined TP53 mRNA in tumor samples from 101 patients with sporadic CRC. Samples were divided...

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Identifiers

PMID: 22373952
DOI: 10.1016/j.gene.2012.02.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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