Article
Co-evolution of rat TAP transporters and MHC class I RT1-A molecules.
Current biology : CB - 29 Jan 1998
Joly E, Le Rolle A F, González A L, Mehling B, Stevens J, Coadwell W J, Hünig T, Howard J C, Butcher G W
Abstract excerpt
The genes for rat major histocompatibility complex (MHC) class I molecules are associated either with those for the A allele of the transporter associated with antigen processing (TAP-A), which can transport peptides with basic carboxy-terminal residues, or with those for TAP-B, which cannot [1-5]. To explore whether these associations have a functional basis, we compared the sequences of 13 rat MHC class la...
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