Article
A novel instance of class I modification (cim) affecting two of three rat class I RT1-A molecules within one MHC haplotype.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jul 2003
González-Muñoz Andrea L, Le Rolle Anne-France, Brun Hélène, Hedrich Hans J, Wedekind Dirk, Powis Simon J, Joly Etienne, Butcher Geoffrey W
Abstract excerpt
MHC class I expression by rats of the RT1(o), RT1(d), and RT1(m) MHC haplotypes was investigated. Identical, functional cDNAs were obtained from RT1(o) and BDIX (RT1(dv1)) rats for three MHC class I molecules. RT1-A1(o/d) and -A2(o/d) are closely related in sequence to other cloned rat class Ia genes that have been shown to map to the RT1-A region, while RT1-A3 degrees is highly homologous to a class I gene...
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