Article
An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III.
Molecular and cellular biology - 1 Jan 1994
Caldecott K W, McKeown C K, Tucker J D, Ljungquist S, Thompson L H
Abstract excerpt
XRCC1, the human gene that fully corrects the Chinese hamster ovary DNA repair mutant EM9, encodes a protein involved in the rejoining of DNA single-strand breaks that arise following treatment with alkylating agents or ionizing radiation. In this study, a cDNA minigene encoding oligohistidine-ta...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- CHO Cells
- Cloning, Molecular
- Cricetinae
- DNA Ligase ATP
- DNA Ligases
- DNA Repair
- DNA, Complementary
- DNA-Binding Proteins
- Humans
- Molecular Sequence Data
- Mutation
- Poly-ADP-Ribose Binding Proteins
- Transfection
- X-ray Repair Cross Complementing Protein 1
- Xenopus Proteins