Article
Identification and functional characterization of Candida albicans CDC4.
Journal of biomedical science - 1 Dec 2005
Shieh Jia-Ching, White Anne, Cheng Yu-Che, Rosamond John
Abstract excerpt
The CDC4 gene of Saccharomyces cerevisiae encodes an essential function that is required for G1-S and G2-M transitions during mitosis and at various stages during meiosis. We have isolated a functional homologue of CDC4 (CaCDC4) from the pathogenic yeast Candida albicans by complementing the S. cerevisiae cdc4-3 mutation with CaCDC4 expressed from its own promoter on a single-copy vector. The predicted product of...
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