Article
Long-term response to interferon therapy in chronic hepatitis B: importance of hepatitis B virus heterogeneity.
Archives of virology. Supplementum - 1 Jan 1993
Santantonio T, Jung M C, Monno L, Milella M, Iacovazzi T, Pape G R, Pastore G, Will H
Abstract excerpt
The long-term therapeutic efficacy of alpha IFN and the influence of preC variants on the type of response were evaluated in 25 patients with chronic hepatitis B, 14 HBeAg and 11 antiHBe positive patients, treated with alpha IFN and monitored for at least four years after discontinuing therapy. I...
Topics
- Alanine Transaminase
- Base Sequence
- DNA Primers
- DNA, Viral
- Follow-Up Studies
- Hepatitis B
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Interferon-alpha
- Molecular Sequence Data
- Mutation