Hepatitis B virus unable to secrete e antigen and response to interferon in chronic hepatitis B.

doi:10.1016/0016-5085(93)90903-p

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Article

Hepatitis B virus unable to secrete e antigen and response to interferon in chronic hepatitis B.

Gastroenterology - 1 Sept 1993

Brunetto M R, Giarin M, Saracco G, Oliveri F, Calvo P, Capra G, Randone A, Abate M L, Manzini P, Capalbo M

Abstract excerpt

BACKGROUND: Anti-hepatitis e antigen-positive chronic hepatitis B is a progressive liver disease associated with precore mutant hepatitis B virus (HBV) and poor response to interferon. Therefore, precore mutant HBV may behave as an interferon-resistant virus. The relations between the prevalences of wild-type and precore mutant HBVs in baseline viremias and response to interferon were analyzed. METHODS: Sera from...

Topics

Adolescent
Adult
Aged
Analysis of Variance
Base Sequence
DNA, Viral
Female
Hepatitis B
Hepatitis B e Antigens
Hepatitis B virus
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Immunohistochemistry

Interferons

Liver

Male

Middle Aged

Molecular Sequence Data

Mutation

Source

Open in PubMed

Identifiers

PMID: 7689519
DOI: 10.1016/0016-5085(93)90903-p

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7689519-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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