Article
Hepatitis B virus unable to secrete e antigen and response to interferon in chronic hepatitis B.
Gastroenterology - 1 Sept 1993
Brunetto M R, Giarin M, Saracco G, Oliveri F, Calvo P, Capra G, Randone A, Abate M L, Manzini P, Capalbo M
Abstract excerpt
BACKGROUND: Anti-hepatitis e antigen-positive chronic hepatitis B is a progressive liver disease associated with precore mutant hepatitis B virus (HBV) and poor response to interferon. Therefore, precore mutant HBV may behave as an interferon-resistant virus. The relations between the prevalences of wild-type and precore mutant HBVs in baseline viremias and response to interferon were analyzed. METHODS: Sera from...
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