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Article

Absence of hepatitis B virus precore mutants in patients with chronic hepatitis B responding to interferon-alpha.

Hepatology (Baltimore, Md.) - 1 Jun 1992

Xu J, Brown D, Harrison T, Lin Y, Dusheiko G

Abstract excerpt

Precore defective HBV mutants may gradually prevail because of immune selection and explain spontaneous seroconversion from HBeAg to anti-HBe in HBV carriers. We have analyzed whether the presence of precore HBV mutants is a determinant of responsiveness to interferon-alpha therapy. Fifteen carriers (nine responders and six nonresponders) who were treated with interferon-alpha were examined. Serum samples were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 1592338
DOI: 10.1002/hep.1840150605

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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