Article
Expressed human immunoglobulin kappa genes and their hypermutation.
European journal of immunology - 1 Dec 1993
Klein R, Jaenichen R, Zachau H G
Abstract excerpt
The question of which germ-line V kappa genes are expressed was studied by sequencing 70 different cDNA clones from a human spleen library and one clone from a fetal liver library. The sequences were compared to a data base containing all germ-line V kappa gene and pseudogene sequences. In additi...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA, Complementary
- Gene Expression
- Gene Rearrangement
- Genes, Immunoglobulin
- Humans
- Immunoglobulin Joining Region
- Immunoglobulin Variable Region
- Immunoglobulin kappa-Chains
- Molecular Sequence Data
- Mutation
- Polymerase Chain Reaction